| Roland Garros French Open (Europe) (En,Fr,De,Es,It,Nl) | |
| Ronaldo V-Football (Europe) (En,Fr,De,Es,It,Pt,Nl) | |
| Ronaldo V-Soccer (USA) (En,Fr,Es,Pt) | |
| Roswell Conspiracies - Aliens, Myths & Legends (Europe) (En,Fr,De) | |
| Roswell Conspiracies - Aliens, Myths & Legends (USA) (En,Fr,De) | |
| Rox (Japan) | |
| Rox (USA, Europe) | |
| RPG Tsukuru GB (Japan) | |
| Rugrats - Time Travelers (USA) | |
| Rugrats - Totally Angelica (USA) | |
| Rugrats - Typisch Angelica (Germany) | |
| Rugrats in Paris - The Movie (Europe) (En,Es) | |
| Rugrats in Paris - The Movie (USA) | |
| Rugrats Movie, The (USA, Europe) | |
| Sabrina - The Animated Series - Spooked! (USA) | |
| Sabrina - The Animated Series - Zapped! (Europe) (En,Fr,De) | |
| Sabrina - The Animated Series - Zapped! (USA, Europe) | |
| Sakata Gorou Kudan no Renju Kyoushitsu (Japan) | |
| Sakura Taisen GB - Geki Hana Kumi Nyuutai! (Japan) | |
| Sakura Taisen GB2 - Thunderbolt Sakusen (Japan) | |
| Samurai Kid (Japan) | |
| Samurai Kid (Japan) [T-En by FlyingClimber & ProstatePunch & Marc_Max v1.0] | |
| San Francisco Rush 2049 (USA) | |
| Sangokushi - Game Boy Ban 2 (Japan) | |
| Sanrio Timenet - Kako Hen (Japan) | |
| Sanrio Timenet - Mirai Hen (Japan) | |
| Santa Claus Junior (Europe) | |
| Saru Puncher (Japan) | |
| Scooby-Doo! - Classic Creep Capers (USA, Europe) | |
| Scrabble (Europe) | |
| SD Hiryuu no Ken EX (Japan) | |
| Sei Hai Densetsu (Japan) | |
| Seme COM Dungeon - Drururuaga (Japan) | |
| Senkai Ibunroku Juntei Taisen - TV Animation Senkaiden Houshin Engi Yori (Japan) | |
| Sesame Street Sports (USA) | |
| Sgt. Rock - On the Frontline (USA) | |
| Shadowgate Classic (USA, Europe) (En,Fr,De,Es,Sv) | |
| Shadowgate Classic (USA, Europe) (En,Fr,De,Es,Sv) (Rev A) | |
| Shadowgate Return (Japan) | |
| Shaman King Card Game - Chou Senjiryakketsu - Funbari Hen (Japan) | |
| Shaman King Card Game - Chou Senjiryakketsu - Meramera Hen (Japan) | |
| Shamus (USA) | |
| Shanghai Pocket (USA, Europe) (Rev A) | |
| Shanghai Pocket (USA) | |
| Shantae (USA) | |
| Shaun Palmer's Pro Snowboarder (USA) | |
| Shin Megami Tensei Devil Children - Aka no Sho (Japan) | |
| Shin Megami Tensei Devil Children - Kuro no Sho (Japan) | |
| Shin Megami Tensei Devil Children - Shiro no Sho (Japan) | |
| Shin Megami Tensei Trading Card - Card Summoner (Japan) | |