| Rijexamen Training 2008 - Code de la Route 2008 (Europe) (Fr,Nl) | |
| Rilakkuma Rhythm - Mattari Kibun de Dararan Ran (Japan) | |
| Ringling Bros. and Barnum & Bailey - Circus Friends - Asian Elephants (USA) | |
| Ringling Bros. and Barnum & Bailey - It's My Circus - Elephant Friend (Europe) (En,Fr,De,Es,It) | |
| Rise of the Guardians (USA) (En,Fr,Es) | |
| Rittai Picross (Japan) | |
| River City - Soccer Hooligans (USA) | |
| River City - Super Sports Challenge (USA) | |
| River King - Mystic Valley (USA) | |
| Riz-Zoawd (Japan) | |
| Road to Vegas (Europe) | |
| Roary the Racing Car (Europe) | |
| Robbie Konijn - Leer Lezen en Schrijven (Netherlands) | |
| Robocalypse (USA) | |
| Robots (Europe) (En,Fr,De,Es,It) | |
| Robots (Japan) | |
| Robots (USA) | |
| Rock Band 3 (Europe) (En,Fr,De,Es,It) | |
| Rock Band 3 (USA) (En,Fr,De,Es,It) | |
| Rock Blast (USA) | |
| Rock Revolution (Europe) (En,Fr,De,Es,It,Sv,No,Da,Fi) | |
| Rock Revolution (USA) (En,Fr,Es) | |
| Rockin' Pretty (USA) | |
| Rockman EXE - Operate Shooting Star (English) | |
| Rockman EXE - Operate Shooting Star (Japan) | |
| Rockman EXE 5 DS - Twin Leaders (Japan) | |
| Rockman Zero Collection (Japan) | |
| Rockman ZX - Advent (Japan) | |
| Rockman ZX (Japan) | |
| Rollercoaster Park (Europe) (En,Fr,Nl) | |
| Rollin' Rascals (USA) | |
| Rondo of Swords (USA) | |
| Roogoo Attack! (USA) (En,Fr,De,Es,It) | |
| Rooms - Fushigi na Ugoku Heya (Japan) | |
| Rooms - The Main Building (Europe) (En,Fr,De,Es,It) | |
| Rooms - The Main Building (USA) (En,Fr,Es) | |
| Rosalina and Luma | |
| Rosario to Vampire - Tanabata no Miss Youkai Gakuen (Japan) | |
| RPG Tkool DS (Japan) (NDSi Enhanced) | |
| Rub Rabbits!, The (Europe) (En,Ja,Fr,De,Es,It) | |
| Rub Rabbits!, The (USA) (En,Ja,Fr,De,Es,It) | |
| Rubik's Puzzle World (Europe) (En,Fr,De,Es,It) | |
| Rubik's World (USA) | |
| Rudolph - The Red-Nosed Reindeer (USA) | |
| Runaway - A Twist of Fate (Europe) (En,Fr,De,Es,It) | |
| Runaway - The Dream of the Turtle (Europe) (En,Fr,De,Es,It) (Rev 1) | |
| Runaway - The Dream of the Turtle (Europe) (En,Fr,De) | |
| Rune Factory - A Fantasy Harvest Moon (Europe) (En,Fr,De,Es,It) | |
| Rune Factory - A Fantasy Harvest Moon (USA) | |
| Rune Factory - Shin Bokujou Monogatari (Japan) | |