| Catz (USA) | |
| Catz 2 - Daisuki Nyan Nyan Park (Japan) | |
| Catz 2 (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da) | |
| Cavallo & Pony - La Scuola di Equitazione (Europe) (Fr,It) | |
| Cedric - L'Anniversaire de Chen (France) | |
| Center Shiken - Eigo Listening - Sokushuu DS (Japan) | |
| Cesar Millan's Dog Whisperer (USA) (En,Fr,Es) | |
| Chajara! Gaeguri Jungsa Keroro - Teullingeurimchatgi Daejakjeon! (Korea) | |
| Challenge Me - Brain Puzzles (Europe) (En,Fr,De,Es,It) | |
| Challenge Me - Brain Puzzles 2 (USA) (En,Fr,Es) | |
| Challenge Me - Maths Workout (Europe) (En,Fr,De,Es,It) | |
| Chameleon - To Dye For! (USA) | |
| Championship Pony (USA) | |
| Chaotic - Shadow Warriors (USA) (En,Fr) | |
| Charlotte's Web (Europe) (En,Fr,De,Es,It) | |
| Charlotte's Web (USA) | |
| Charm Girls Club - My Fashion Mall (Europe) (En,Fr,Es) | |
| Charm Girls Club - My Fashion Mall (USA) (En,Fr,Es) | |
| Charm Girls Club - My Fashion Show (Europe) (En,Fr,Es) | |
| Charm Girls Club - My Fashion Show (USA) (En,Fr,Es) | |
| Charm Girls Club - My Perfect Prom (Europe) (En,Fr,Es) | |
| Charm Girls Club - My Perfect Prom (USA) (En,Fr,Es) | |
| Charm Girls Club - Watashi no Fashion Mall (Japan) | |
| Charm Girls Club - Watashi no Fashion Show (Japan) | |
| Chase, The - Felix Meets Felicity (Europe) (En,Fr,De,Es,It) | |
| Chase, The - Felix Meets Felicity (USA) (En,Fr,De,Es,It) | |
| Cheer We Go (USA) (NDSi Enhanced) | |
| Cheetah Girls, The - Passport to Stardom (USA) | |
| Cheetah Girls, The - Pop Star Sensations (USA) | |
| Chess (Europe) (En,Fr,De,Es,It) | |
| Chess for Kids (Europe) (En,Fr,De,Es,It) | |
| Chessmaster - The Art of Learning (Europe) (En,Fr,De,Es,It,Nl) | |
| Chessmaster - The Art of Learning (USA) (En,Fr,Es) | |
| Chi's Sweet Home - Chi ga Ouchi ni Yatte Kita (Japan) | |
| Chibi Maruko-chan DS - Maru-chan no Machi (Japan) | |
| Chibi-Robo! - Park Patrol (USA) | |
| Chicken Attack DS (Europe) (En,Fr,De) | |
| Chicken Blaster (Europe) (En,Fr,De,Es,It) | |
| Chicken Hunter (USA) (En,Fr,De,Es,It,Nl) | |
| Chicken Little - Ace in Action (Europe) (En,Fr,De,Es,It) | |
| Chicken Little - Ace in Action (USA) | |
| Chicken Little - Uchuu Saikyou no Team (Japan) | |
| Chicken Shoot (Europe) (En,Fr,De,Es,It) | |
| Chicken Shoot (USA) (En,Fr,De,Es,It) | |
| Chiffres et des Lettres, Des - L'Entrainement Cerebral Maximum! (France) | |
| Chikyuu no Arukikata DS - France '07-'08 (Japan) | |
| Chikyuu no Arukikata DS - Hawaii '07-'08 - Oahu-tou (Japan) | |
| Chikyuu no Arukikata DS - Hong Kong '07-'08 (Japan) | |
| Chikyuu no Arukikata DS - Igirisu '07-'08 (Japan) | |
| Chikyuu no Arukikata DS - Italia '07-'08 - Roma, Milano, Firenze, Venezia (Japan) | |