| Puzzle Series Vol. 8 - Nankuro (Japan) | |
| Puzzle Series Vol. 9 - Sudoku 2 Deluxe (Japan) | |
| Puzzle Time (USA) | |
| Puzzler Collection (Europe) | |
| Puzzler Collection (USA) | |
| Puzzler World (Europe) | |
| Puzzler World 2011 (Europe) | |
| Quest Braintainment (Netherlands) | |
| Quest Trio, The - Jewels, Cards and Tiles (Europe) (Fr,Nl) | |
| Quest Trio, The - Jewels, Cards and Tiles (USA) | |
| Questions pour un Champion - Le Jeu Officiel - Edition Speciale 20 Ans (France) | |
| Quick Yoga Training - Learn in Minutes a Day (USA) (En,Fr,De,Es,It) | |
| QuickSpot (USA) | |
| Quiz & Touch Kensaku - Mushi Zukan DS - Mushi o Sagasou Shirabeyou (Japan) | |
| Quiz Kirameki Star Road (Japan) | |
| Quiz Magic Academy DS - Futatsu no Jikuuseki (Japan) | |
| Quiz Magic Academy DS (Japan) | |
| Quiz Magic Academy DS (Japan) (Rev 1) | |
| Quiz no Tabi - Tetsudou Ryojou Hen (Japan) | |
| Quiz Taxi (Germany) | |
| Quiz! Hexagon II (Japan) | |
| Quiz! Nihongo-ou (Japan) | |
| Rabbids Go Home - A Comedy Adventure (USA) (En,Fr,Es) (NDSi Enhanced) | |
| Rabbids Go Home (Europe) (En,Fr,De,Es,It,Nl) (NDSi Enhanced) | |
| Rabbids Party - TV Party (Japan) | |
| Race Driver - Create & Race (Europe) (En,Fr,De,Es,It) | |
| Race Driver - Create & Race (USA) (En,Fr,De,Es,It) | |
| Race Driver - Grid (Europe) (En,Fr,De,Es,It) | |
| Radiant Historia (Japan) | |
| Radiant Historia (USA) | |
| Rafa Nadal Tennis (Europe) (En,Fr,De,Es,It) | |
| Rafa Nadal Tennis (USA) (En,Fr) | |
| Ragnarok DS (Korea) | |
| Ragnarok DS (USA) | |
| Ragnarok Online DS (Japan) | |
| Rain Drops (USA) | |
| Rainbow Islands Revolution (Europe) | |
| Rainbow Islands Revolution (USA) | |
| Raku Raku Shindenzu Training DS (Japan) (Rev 1) | |
| Rango (Europe) (En,Fr,De,Es,It) | |
| Ratatouille - Food Frenzy (Europe) (En,Fr,De,Es,It,El) | |
| Ratatouille - Food Frenzy (USA) | |
| Ratatouille (Europe) | |
| Ratatouille (Europe) (En,Sv,No,Da) | |
| Ratatouille (Europe) (Es,Pt) | |
| Ratatouille (Europe) (Fr,Nl) | |
| Ratatouille (Europe) (It,El) | |
| Ratatouille (Germany) | |
| Ratatouille (USA) | |
| Rayman - Raving Rabbids - TV Party (Europe) (En,Fr,De,Es,It,Nl) | |