| Miss Spider's Sunny Patch Friends - Harvest Time Hop and Fly (USA) (En,Fr,Es) | |
| Mission Hurry Up, Mario Bros. | |
| Mission Runway (USA) | |
| Mister Slime (USA) (En,Fr,Es) | |
| Mitamekara Yomigaeru - Otona no Kikonashi Training (Japan) | |
| Miteha Ikenai (Japan) | |
| Mitsukete! Keroro Gunsou - Machigai Sagashi Daisakusen de Arimasu! (Japan) | |
| Miyamoto Sansuu Kyoushitsu no Kyouzai - Kashikoku Naru Puzzle DS Ban (Japan) | |
| Mizuiro Blood (Japan) | |
| MLB Power Pros 2008 (USA) | |
| Moe Moe 2-ji Taisen(ryaku) Two - Yamato Nadeshiko (Japan) | |
| Moe Sta - Moeru Toudai Eigojuku (Japan) | |
| Moemon Black 2 | |
| Moemon Heart of Gold | |
| Moemon Platinum | |
| Moemon White 2 | |
| Moero! Nekketsu Rhythm Damashii - Osu! Tatakae! Ouendan 2 (Japan) | |
| Moetan DS (Japan) | |
| Mogitate Tingle no Barairo Rupee Land (Japan) | |
| Mokjjangiyagi - Colobockle Station (Korea) | |
| Mokjjangiyagi - Colobockle Station for Girl (Korea) | |
| Mokjjangiyagi - Neowa hamkke Jaraneun Seom (Korea) | |
| Momotarou Dentetsu - 20 Shuunen (Japan) | |
| Momotarou Dentetsu - World (Japan) | |
| Momotarou Dentetsu DS - Tokyo & Japan (Japan) | |
| Momotarou Dentetsu DS - Tokyo & Japan (Japan) (Rev 1) | |
| Mon Coach Personnel - J'Ameliore Mon Anglais (France) | |
| Mon Coach Personnel - J'Ameliore Mon Espagnol (France) | |
| Mon Coach Personnel - J'Enrichis Mon Vocabulaire (France) | |
| Mon Coach Personnel - Mes Recettes Plaisir et Ligne (France) (NDSi Enhanced) | |
| Mon Premier Bescherelle (France) | |
| Mondai na Nihongo (Japan) | |
| Monmallineun 3-gongjuwa Hamkkehaneun - Geurimyeonsang Yeongdaneo Amgibeop (Korea) | |
| Monokuro Boo & Baby Boo - Kururin Boo (Japan) | |
| Monopoly (Europe) (En,Fr,De) | |
| Monopoly (USA) (En,Fr) | |
| Monster Bomber (Europe) (En,Fr,De,Es,It) | |
| Monster Bomber (Japan) | |
| Monster Bomber (USA) | |
| Monster Farm DS 2 - Yomigaeru! Master Breeder Densetsu (Japan) | |
| Monster Frenzy (USA) (En,Fr,Es) | |
| Monster High - 13 Wishes (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da,Fi) | |
| Monster High - 13 Wishes (USA) (En,Fr,Es) | |
| Monster High - Ghoul Spirit (Europe) (En,Fr,De,Es,It,Nl) (NDSi Enhanced) | |
| Monster High - Ghoul Spirit (USA) (En,Fr) (NDSi Enhanced) | |
| Monster High - Skultimate Roller Maze (Europe) (En,Fr,De,Es,It,Nl,Sv,No,Da,Fi) | |
| Monster High - Skultimate Roller Maze (USA) (En,Fr,Es) | |
| Monster House (Europe) | |
| Monster House (Europe) (En,Fr,De,Es,It,Sv,Da) | |
| Monster House (Japan) | |