| Affari Tuoi (Italy) | |
| AFL Mascot Manor (Australia) | |
| Again - FBI Chou Shinri Sousakan (Japan) | |
| Again - Interactive Crime Novel (USA) | |
| Agatha Christie - The ABC Murders (Europe) (En,Fr,De,Es,It) | |
| Agatha Christie - The ABC Murders (Europe) (En,Fr,De,Es,Nl) | |
| Agatha Christie - The ABC Murders (USA) (En,Fr,Es) | |
| Age of Empires - Mythologies (Europe) (En,Fr,De,Es,It) | |
| Age of Empires - Mythologies (USA) (En,Fr) | |
| Age of Empires - The Age of Kings (Europe) (En,Es,It) | |
| Age of Empires - The Age of Kings (Europe) (En,Fr,De) | |
| Age of Empires - The Age of Kings (USA) | |
| Aibou DS (Japan) | |
| Air Traffic Chaos (USA) | |
| Akachan wa Doko kara Kuru no (Japan) | |
| Akagawa Jirou Mystery - Tsuki no Hikari - Shizumeru Kane no Satsujin (Japan) | |
| Akagawa Jirou Mystery - Yasoukyoku - Hon ni Manekareta Satsujin (Japan) | |
| Akai Ito Destiny DS (Japan) | |
| Akai Ito DS (Japan) | |
| Akko de Pon! - Ikasama Hourouki (Japan) | |
| Akko ni Omakase! - Brain Shock (Japan) | |
| Akogare Girls Collection - Lovely Youchien Nikki (Japan) | |
| Akogare Girls Collection - Suteki ni Nurse Days (Japan) | |
| Akumajou Dracula - Gallery of Labyrinth (Japan) | |
| Akumajou Dracula - Sougetsu no Juujika (Japan) (Rev 1) | |
| Akumajou Dracula - Ubawareta Kokuin (Japan) | |
| ALC no 10-punkan Eigo Master - Chuukyuu (Japan) | |
| ALC no 10-punkan Eigo Master - Joukyuu (Japan) (Rev 1) | |
| ALC no 10-punkan Eigo Master - Shokyuu (Japan) | |
| Alex Rider - Stormbreaker (Europe) | |
| Alex Rider - Stormbreaker (Europe) (En,Fr,De,Es) | |
| Alex Rider - Stormbreaker (USA) | |
| Alice in Wonderland (Europe) (En,Fr,De,Es,It,Nl) (NDSi Enhanced) | |
| Alice in Wonderland (USA) (En,Fr,Es) (NDSi Enhanced) | |
| Aliens in the Attic (Europe) (En,Fr,De,Es,It,Nl) | |
| Aliens in the Attic (USA) (En,Fr,De,Es,It,Nl) | |
| All Star Cheer Squad (USA) | |
| All Star Cheerleader (Europe) (En,De,Es) | |
| Allied Ace Pilots (Europe) (En,Fr,De,Es,It) | |
| Alpha and Omega (Europe) (En,Fr,De,Es,It) | |
| Alssongdalssong - Myeonghwatamheom DS (Korea) | |
| Alvin and the Chipmunks - Chipwrecked (Europe) | |
| Alvin and the Chipmunks - Chipwrecked (Europe) (Fr,De,Es,It) | |
| Alvin and the Chipmunks - Chipwrecked (USA) (En,Fr) | |
| Alvin and the Chipmunks - The Squeakquel (Europe) (En,Fr,De) | |
| Alvin and the Chipmunks - The Squeakquel (USA) | |
| Alvin and the Chipmunks (Europe) (En,Fr,De,Es,It) | |
| Alvin and the Chipmunks (USA) (En,Fr) | |
| Aly & AJ Adventure, The (Europe) (En,Fr,De,Es,It) | |
| Aly & AJ Adventure, The (USA) | |